Additional file 1 of Integration of multi-omics data to unveil the molecular landscape and role of piRNAs in early-onset colorectal cancer

Additional file 1: Table S1. Sequences of qPCR primers. Table S2. Clinical and tumor characteristics of patients with early-onset and late-onset colorectal cancer. Table S3. GSEA analysis of the different expression genes. Table S4. Differentially expressed genes identified in the TCGA database after using inverse probability of treatment weighting method to balance baseline covariates associated with EOCRC and LOCRC. Table S5. Consistent differential methylation sites and transcription genes identified in the TCGA database. Table S6. Baseline information of CRC patients. Table S7. RNA sequences of differentially expressed piRNAs and their IDs in piRBase, piRNAdb and RNAcentral. Table S8. GSEA analysis of RNA-seq results (mimic-FR019089 vs mimic-NC). Table S9. GSEA analysis of RNA-seq results (mimic-FR019019 vs mimic-NC).