Transcriptional responses of the human dorsal striatum in opioid use disorder implicates cell type-specifc programs

Gene expression profile at single cell level of striatal cells from the caudate nucleus and putamen in postmortem human brains of unaffected individuals or those with opioid use disorder. Overall design: Case-cohort matched postmortem human brain single nucleus RNA-seq of the caudate nucleus and putamen of individuals with and without opioid use disorder