ProteinGym

ProteinGym is a benchmark suite for assessing the performance of protein fitness prediction and design models. It comprises a large curated collection of 200+ high-throughput experimental assays (~3M mutated sequences), as well as clinical annotations from experts about the pathogenicity of mutants in over 3k human genes.

ProteinGym是一款用于评估蛋白质适应性预测与设计模型性能的基准测试套件。该套件涵盖200余项经精心整理（curated）的高通量实验检测数据集，包含约300万条突变序列；同时收录了来自专家的、针对超过3000个人类基因中突变体致病性的临床注释信息。