Study design and biopsy sampling.

Throughout this figure, white indicates time off NSAIDs and gray indicates time on NSAIDs. (Panel A) Thirteen individuals with BE, showing times of endoscopies as black x's, and indicating time on and off NSAIDs. (Panel B) The temporal and spatial location of all biopsies in the study. Red lines show the extent of Barrett's segment from the gastroesophageal junction (GEJ) to the squamocolumnar junction (SCJ). The Y-axis is measured in cm from the GEJ. The X-axis is scaled in years of follow-up, with the total amount of follow-up for each individual indicated below the data for that individual. Small black circles indicate the locations of the biopsies that were assayed in this study.