Combined analysis of mRNA and miRNA reveals the mechanism of pacific white shrimp (Litopenaeus vannamei) under acute alkalinity stress

In this study, we aimed to explore the response mechanism to acute high-alkaline stress by RNA-seq at low-alkaline (50 mg/L) and high-alkaline (350 mg/L). The results revealed that pacific white shrimp under alkalinity stress, genes related to ion regulation, digestion, metabolism and immunity were more prominent to the response. We identified 215 differentially expressed mRNAs (DEGs) and 35 DEMs, of which 180 DEGs, 28 DEMs were up-regulated and 35 DEGs, 7 DEMs were down-regulated, respectively.