Targeting PRDX6-dependent localization and function of GPX4 enhances ferroptosis-mediated tumor suppression

Mendeley Data2026-04-09 收录

铁死亡机制

肿瘤靶向治疗

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The relevant data of the article ：Targeting PRDX6-dependent localization and function of GPX4 enhances ferroptosis-mediated tumor suppression

SAM Competitive PRMT5 Inhibitor PF-06939999 Demonstrates Antitumor Activity in Splicing Dysregulated NSCLC with Decreased Liability of Drug Resistance

肿瘤靶向治疗

药物耐药机制

Protein arginine methyltransferase 5 (PRMT5) over-expression in hematological and solid tumors methylates arginine residues on cellular proteins involved in important cancer functions including cell c

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DataSheet_10_High expression level of the FTH1 gene is associated with poor prognosis in children with non-M3 acute myeloid leukemia.zip

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Acute myelogenous leukemia (AML) is a disease that severely affects the physical health of children. Thus, we aimed to identify biomarkers associated with AML prognosis in children. Using transcriptom

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Table_6_Identification of biomarkers co-associated with M1 macrophages, ferroptosis and cuproptosis in alcoholic hepatitis by bioinformatics and experimental verification.xlsx

非酒精性脂肪性肝炎生物标志物

铁死亡机制

BackgroundsAlcoholic hepatitis (AH) is a major health problem worldwide. There is increasing evidence that immune cells, iron metabolism and copper metabolism play important roles in the development o

NIAID Data Ecosystem00

肿瘤靶分子临床研究信息数据集

肿瘤靶向治疗

临床研究

聚焦肿瘤靶分子临床研究全流程，整合靶点发现、临床试验设计、疗效数据、安全性评估等核心信息。数据经标准化清洗与专业校验，关联靶点分子结构、作用机制及临床结果，支持科研机构靶点验证、药企药物研发、临床机构方案优化，为靶分子临床转化提供高质量、可溯源的数据支撑。

江苏数据交易所80

DataSheet_1_Huaier suppresses pancreatic cancer progression via activating cell autophagy induced ferroptosis.zip

胰腺癌治疗

铁死亡机制

PurposeThe anti-tumour effect of Huaier has been demonstrated in a variety of tumours. Ferroptosis is a newly identified type of programmed cell death accompanied by the accumulation of reactive oxyge

NIAID Data Ecosystem20

Targeting PRDX6-dependent localization and function of GPX4 enhances ferroptosis-mediated tumor suppression

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