CPDB

The Carcinogenic Potency Database (CPDB) is a unique and widely used international resource of the results of 6540 chronic, long-term animal cancer tests on 1547 chemicals. The CPDB provides easy access to the bioassay literature, with qualitative and quantitative analyses of both positive and negative experiments that have been published over the past 50 years in the general literature through 2001 and by the National Cancer Institute/National Toxicology Program through 2004. The CPDB standardizes the diverse literature of cancer bioassays that vary widely in protocol, histopathological examination and nomenclature, and in the published author’s choices of what information to provide in their papers. Results are reported in the CPDB for tests in rats, mice, hamsters, dogs, and nonhuman primates.

搜集汇总

背景与挑战

背景概述

CPDB（致癌性潜力数据库）是一个国际资源，汇总了6540项针对1547种化学物质的慢性动物癌症测试结果，涵盖过去50年的文献数据。该数据库提供定性和定量分析，标准化了差异较大的生物测定文献，并包括大鼠、小鼠等多种动物的实验信息，用于评估化学物质的致癌潜力。