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Crystal structure of the human eIF4A1-ATP analog-RocA-polypurine RNA complex

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Protein Data Bank Japan2023-11-22 更新2026-03-21 收录
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Crystal structure of the human eIF4A1-ATP analog-RocA-polypurine RNA complex Descriptor: (1R,2R,3S,3aR,8bS)-6,8-dimethoxy-3a-(4-methoxyphenyl)-N,N-dimethyl-1,8b-bis(oxidanyl)-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxamide, Eukaryotic initiation factor 4A-I, MAGNESIUM ION, ... Authors: Iwasaki, W, Takahashi, M, Sakamoto, A, Iwasaki, S, Ito, T. Deposit date: 2018-02-16 Release date: 2019-01-16 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2 Å) Cite: The Translation Inhibitor Rocaglamide Targets a Bimolecular Cavity between eIF4A and Polypurine RNA. Mol. Cell, 73, 2019
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2018-02-16
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