Aryl N-acetamide compounds exert antimalarial activity by acting as agonists of rhomboid protease PfROM8 and cation channel PfCSC1
收藏NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/sra/ERP170432
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资源简介：
Plasmodium falciparum malaria parasites were challenged with Medicines for Malaria Venture compound MMV020512, until the parasites developed resistance. Genome sequencing of the resistant parasite genomes revealed mutations in the genes for a rhomboid protease ROM8, or a cation transporter CSC1
创建时间：
2025-07-18
