Single cell analysis in the adult aorta after Tie2 deletion

To analyze the Angiopoietin receptor Tie2 on the arterial endothelial cells during atheroclerosis Overall design: We analyzed total aortic cells from arterial Tie2 deleted mice during homeostasis and during atheroclerosis. To understand the difference between Tie2 and Tie1 during plaque formation, we also analyzed total aortic cells from both aortic arch and throcic/abdominal aorta during atheroclerosis