N-251 exhibits leishmanicidal activity against different L. donovani complex parasites.

Figshare2019-03-25 更新2026-04-29 收录

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https://figshare.com/articles/dataset/N-251_exhibits_leishmanicidal_activity_against_different_i_L_i_i_donovani_i_complex_parasites_/7887959 数据链接链接失效反馈

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N-251 exhibits leishmanicidal activity against different L. donovani complex parasites.

创建时间：

2019-03-25

Targeting the Trypanothione Reductase of Tissue-Residing Leishmania in Hosts’ Reticuloendothelial System: A Flexible Water-Soluble Ferrocenylquinoline-Based Preclinical Drug Candidate

抗利什曼病药物

二茂铁衍生物

Since inception, the magic bullets developed against leishmaniasis traveled a certain path and then dropped down due to either toxicity or the emergence of resistance. The route of administration is a

NIAID Data Ecosystem80

Zipped folder with data spreadsheets for Leishmania inhibitory concentrations (leishmania_ic50) and nectar and pollen flavonoid concentrations (nectar.pollen.flavonoids).

抗利什曼病药物

植物黄酮类化合物分析

(ZIP)

NIAID Data Ecosystem40

Repositioning Antitubercular 6‑Nitro-2,3-dihydroimidazo[2,1‑b][1,3]oxazoles for Neglected Tropical Diseases: Structure–Activity Studies on a Preclinical Candidate for Visceral Leishmaniasis

药物重定位

抗利什曼病药物

6-Nitro-2,3-dihydroimidazo[2,1-b][1,3]oxazole derivatives were initially studied for tuberculosis within a backup program for the clinical trial agent pretomanid (PA-824). Phenotypic screening of r

Figshare2016-03-18 更新30

In vitro drug susceptibility of a panel of recent clinical L . infantum isolates against antileishmanial reference drugs in THP-1, bone-marrow derived macrophages (BMMφ) and mouse peritoneal exudative cells (PEC).

抗利什曼病药物

寄生虫药效评估

Intracellular amastigote drug susceptibility against miltefosine (MIL), paromomycin (PMM), pentavalent antimonials (SbV), trivalent antimonials (SbIII) and amphotericin B (AmB). The presented IC50-val

NIAID Data Ecosystem60

Synthesis, Biological Evaluation, Structure–Activity Relationship, and Mechanism of Action Studies of Quinoline–Metronidazole Derivatives Against Experimental Visceral Leishmaniasis

抗利什曼病药物

构效关系

In our efforts to identify novel chemical scaffolds for the development of antileishmanial agents, a series of quinoline–metronidazole hybrid compounds was synthesized and tested against the murine mo

NIAID Data Ecosystem40

N-251 exhibits leishmanicidal activity against different L. donovani complex parasites.

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