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CryoEM structure of Gq-coupled MRGPRX4 with small molecule agonist MS47134

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Protein Data Bank Japan2025-06-04 更新2026-05-23 收录
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CryoEM structure of Gq-coupled MRGPRX4 with small molecule agonist MS47134 Descriptor: Gs-mini-Gq chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... Authors: Cao, C, Fay, J.F, Gumpper, R.H, Roth, B.L. Deposit date: 2021-09-18 Release date: 2021-11-17 Last modified: 2025-06-04 Method: ELECTRON MICROSCOPY (2.6 Å) Cite: Structure, function and pharmacology of human itch GPCRs. Nature, 600, 2021

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2021-09-18
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