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Crystal structure of the GluA2 ligand-binding domain (S1S2J-L483Y-N754S) in complex with glutamate and BPAM-344 at 1.87 A resolution

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Protein Data Bank Japan2024-11-06 更新2026-03-21 收录
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Crystal structure of the GluA2 ligand-binding domain (S1S2J-L483Y-N754S) in complex with glutamate and BPAM-344 at 1.87 A resolution Descriptor: 4-cyclopropyl-7-fluoro-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide, ACETATE ION, CACODYLATE ION, ... Authors: Noerholm, A.B, Frydenvang, K, Kastrup, J.S. Deposit date: 2013-10-01 Release date: 2013-11-20 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.87 Å) Cite: Synthesis, pharmacological and structural characterization, and thermodynamic aspects of GluA2-positive allosteric modulators with a 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide scaffold. J.Med.Chem., 56, 2013
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2013-10-01
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