Loss of FSTL1 in the Myf5 lineage causes brown adipose tissue atrophy

NIAID Data Ecosystem2026-03-14 收录

棕色脂肪组织

基因功能缺失分析

数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP257231 数据链接链接失效反馈

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资源简介：

Aim to investigate the role of FSTL1 in brown adipose tissue (BAT) development and function Overall design: Bulk RNA sequencing of the total interscapular BAT depot from newborn wildtype and Myf5-Fstl1 KO mice

创建时间：

2022-12-01

Whole genome DNA methylation analysis with reduced representation bisulfite sequencing (RRBS) to identify Myod1 promoter methylation in brown adipose tissues of D1KO and their respective wild type control mice. Whole genome DNA methylation analysis with reduced representation bisulfite sequencing (RRBS) to identify Myod1 promoter methylation in brown adipose tissues of D1KO and their respective wild type control mice

甲基化分析

棕色脂肪组织

Our RRBS profiling indicated that the methylation rate at the proximate promoter and 5’-region of Myod1 gene was significantly decreased in brown adipose tissues of D1KO mice compared to their respect

NIAID Data Ecosystem120

Transcriptome profiling of NGLY1 deficient K562 cells. Transcriptome profiling of NGLY1 deficient K562 cells

基因功能缺失分析

疾病转录组学

The data includes a transcriptome analysis of K562 cell lines in which the gene N-glycanase 1 (NGLY1) was mutated in exon 1 and/or exon 3 to include loss of function mutations as described in Mueller

NIAID Data Ecosystem50

Transcriptomic profiling of wild-type C2C12 cells and C2C12 cells with Myod1 gene knockout by RNA-sequencing. Transcriptomic profiling of wild-type C2C12 cells and C2C12 cells with Myod1 gene knockout by RNA-sequencing

肌肉分化转录组学

基因功能缺失分析

C2C12 is a myoblast cell line usually used for study of muscle differentiation. Myod1 is a pro-differentiation factor for myogenesis. We found that CRISPR/Cas9-mediated Myod1 gene knockout in C2C12 ce

NIAID Data Ecosystem30

gene-expression profiling between UBE2S knock down A375 cells and control A375 cells. gene-expression profiling between UBE2S knock down A375 cells and control A375 cells

基因功能缺失分析

癌细胞转录组

investigate the gene expression change between UBE2S konck down A375 cells mediated by Lentivirus and control A375 cells. Overall design: In the study, melanoma A375 cell line was selected and transfe

NIAID Data Ecosystem70

Identification and characterization of distinct brown adipocyte subtypes in C57BL/6J mice

单细胞转录组学

棕色脂肪组织

Here we provide scRNAseq data from the stromal vascular fraction of adult (8 weeks) murine brown adipose tissue. This allows studying cellular composition and cellular heterogeneity within brown fat.

NIAID Data Ecosystem40

Loss of FSTL1 in the Myf5 lineage causes brown adipose tissue atrophy

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