Crystal structure of P38 alpha in complex with DP437
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Crystal structure of P38 alpha in complex with DP437 Descriptor: 1-{3-tert-butyl-1-[4-(hydroxymethyl)phenyl]-1H-pyrazol-5-yl}-3-naphthalen-1-ylurea, Mitogen-activated protein kinase 14 Authors: Abendroth, J. Deposit date: 2010-06-24 Release date: 2010-09-15 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Switch control pocket inhibitors of p38-MAP kinase. Durable type II inhibitors that do not require binding into the canonical ATP hinge region Bioorg.Med.Chem.Lett., 20, 2010
创建时间：
2010-06-24
