Idh3a

Predicted to enable isocitrate dehydrogenase (NAD+) activity and magnesium ion binding activity. Predicted to be involved in isocitrate metabolic process and tricarboxylic acid cycle. Located in mitochondrion and myelin sheath. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in retinitis pigmentosa 90. Orthologous to human IDH3A (isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha). [provided by Alliance of Genome Resources, Nov 2024]

预测该基因产物可激活异柠檬酸脱氢酶（NAD+）活性和镁离子结合活性。预测该基因产物参与异柠檬酸代谢过程和三羧酸循环。该基因产物定位于线粒体和髓鞘。在多个结构中表达，包括消化系统；中枢神经系统；泌尿生殖系统；呼吸系统；以及感觉器官。该基因的人类同源基因与视网膜色素变性90相关。与人类IDH3A（异柠檬酸脱氢酶（NAD(+)) 3催化亚基α）同源。[由基因组资源联盟提供，2024年11月]