Data set and results of regression analysis of gene variants in Prostate Cancer patients from Mexico-mestizo population.

Genotyping assays were performed using TaqMan SNP Genotyping Assays probes C_27532228_20 and C_2362601_10 (Life Technologies, Carlsbad, CA, USA). Thermalcycler: StepOnePlus™ Real-Time PCR (Thermo Fisher Scientific, Waltham, MA, USA). Sample: genomic DNA from blood. Subjects: Prostate cancer patients and controls (healthy and benign prostatic hyperplasia). Results of Regression Anlysis for clinical features of gene SRD5A2 variants (rs9282858 and<strong> </strong>rs523349) in prostate cancer patients from Mexican-mestizo population. Starting with the full model, successive models are created, each one using one less regressor (or covariate) than the previous model. Each of the regressors currently in the model is removed to create a "trial" model excluding that regressor. The p-value of the current model (or full model) versus the trial model (or reduced model) is calculated, and the model with the smallest p-value is used as the next model. This method removes the least significant variable from the current model. If every p-value is smaller than the p-value cut off specified, the backward elimination method stops. The method also stops if all variables have been removed from the model, or if all variables left are included in the original reduced model. From the standpoint of further analysis, the final model becomes the "full model" for this set of potential regressors Ethics approval and consent to participate in the study: The protocol and informed consent were approved by the Ethics and Research Committee of the School of Medicine (Universidad Autonoma de Nuevo Leon), with registration number UR16-00007. In the data set, no data was included that compromises the confidentiality of the participating subjetcs. <pre> </pre>