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Enantioselective Synthesis of Bicyclo[2.2.2]octenones Using a Copper-Mediated Oxidative Dearomatization/[4 + 2] Dimerization Cascade

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https://figshare.com/articles/dataset/Enantioselective_Synthesis_of_Bicyclo_2_2_2_octenones_Using_a_Copper_Mediated_Oxidative_Dearomatization_4_2_Dimerization_Cascade/2954110
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An enantioselective approach to bicyclo[2.2.2]octenone structures utilizing a copper-mediated asymmetric oxidative dearomatization/[4 + 2] dimerization cascade is described. The total synthesis and absolute stereochemistry reassignment of (+)-aquaticol has been achieved using the methodology.
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2016-06-03
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