Dnmt2 Attenuates Diarrhea-Predominant Irritable Bowel Syndrome via tRNA Fragment-Mediated Suppression of Trpv1 and Htr3a

Data DescriptionThis dataset contains the raw experimental data and unedited images supporting the findings of the manuscript titled "Dnmt2 Attenuates Diarrhea-Predominant Irritable Bowel Syndrome via tRNA Fragment-Mediated Suppression of Trpv1 and Htr3a". The data is organized into four main archives corresponding to the figures and supplementary materials in the manuscript.File Structure & Content Guide:1. IHC.zip (Immunohistochemistry Data)Contains all original immunohistochemistry staining images.Organization: Files are sorted by figure number and gene name.Naming Convention: Folders are named as "Fig. X [gene name]" (e.g., Fig.1F ChgA). Please refer to the folder names to locate the specific staining results mentioned in the manuscript.2. Raw Data.zip (Numerical Data for Graphs)Contains the original numerical values used to generate all statistical graphs and charts in the main text.Organization: Excel files are named according to the corresponding Figure panels. The file includes the raw data points.3. Western Blot Raw Data.zip (Unedited Blot Images)Contains full-length western blot membranes.Content: Includes complete blots with molecular weight markers visible for all proteins analyzed. Cropped regions presented in the main figures are indicated within these full-membrane scans.4. Supplementary Data.zip (Supplementary Materials)Contains additional raw data, uncropped images, or extended datasets referenced in the supplementary information section of the manuscript.All data provided here represents the unprocessed, primary records generated during the study. For any inquiries regarding specific data points or experimental conditions, please contact the corresponding author.