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Resolve smFISH spatial transcriptomics on the GL261 tumor bearing hemisphere, treated with PBS / aPD1 / CSI / CSI+aPD1

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE292668
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We performed Resolve Molecular Cartography to assess the effect of CpG-STAT3ASO+anti-PD1 therapy on immune cells from GL261 high grade glioma model. The mice were implanted with GL261 cells. Subsequently, the mice received four intracranial treatments with either PBS, anti-PD1, CpG-STAT3ASO, or CpG-STAT3ASO combined with anti-PD1, and were sacrificed on day 21. Brains were isolated.
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2025-08-20
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