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Students’ academic and social adaptation is linked to factors such as their initial study motivations, the atmosphere of the academic environment and their perception of academic wellbeing. This paper analyses the initial adaptation of first-degree students in their first semester through a quantitative ex post facto study with a descriptive-exploratory approach, using a questionnaire as the information-gathering instrument. Findings shed light on the concept of initial adaptation itself (through the creation of an index) and validate the study of the construct through three factors: initial motivation, the academic environment and perception of academic wellbeing. Also, the influence on initial adaptation of the academic and social context of the degree course taken is demonstrated:, as the constitutive features of the degree contribute information predicting how students will integrate into the institution. Therefore, it is suggested that institutional means and actions should be designed and put in place in accordance with measurements that indicate how students function best in a specific context (the bachelor’s degree), in order to boost motivation and the perception of academic wellbeing.