High-throughput 3' DGE library preparation was conducted as per: dx.doi.org/10.17504/protocols.io.bumynu7w with 6 nucleotide barcodes on R2 for the 384 wells.Reads were demultiplexed using a cust
Epigenetic modifiers are promising targets to improve therapies in patients with cancer. Targeting the methyltransferase DOT1L with small molecule inhibitors has shown promising effects on the control