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Transcriptomic profile of cohesin proficient and deficient cells

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE125202
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The goal of this study is to identify the mechanism underlying the notion that loss of cohesin complex could sensitize tumor cells to anti-PD-1 therapy. mRNA profiles of WT, NIPBL Knockout, SMC1A knockdown HCT116 cells and WT, Nipbl knockout, Stag2 knockout CT26 cells were detected by RNA-Sequencing. Duplicate for each knockout or knockdown group.
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2022-01-14
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