Activation of endogenous retroviruses and induction of viral mimicry by MEK1/2 inhibition in pancreatic cancer

NIAID Data Ecosystem2026-05-01 收录

胰腺癌治疗

抑制机制

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE238200 数据链接链接失效反馈

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This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

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2024-04-04

Radiosensitizing pancreatic cancer with PARP inhibitor and gemcitabine: an in vivo and a whole-transcriptome analysis after proton or photon irradiation

胰腺癌治疗

转录组分析

RNA sequencing profiling showed differentially expressed genes implicated in categories such as DNA repair, type I interferon signaling and cell cycle. Moreover, a large amount of lncRNA were dysregul

干细胞与再生医学数据中心2022-02-20 更新80

Reversible Monoacylglycerol Lipase Inhibitors: Discovery of a New Class of Benzylpiperidine Derivatives

药物靶点发现

胰腺癌治疗

Monoacylglycerol lipase (MAGL) is the enzyme responsible for the metabolism of 2-arachidonoylglycerol in the brain and the hydrolysis of peripheral monoacylglycerols. Many studies demonstrated benefic

NIAID Data Ecosystem60

Dithiocarbazate-Copper Complexes for Bioimaging and Treatment of Pancreatic Cancer

胰腺癌治疗

铜配合物生物成像

Anticancer agents that present nonapoptotic cell death pathways are required for treating apoptosis-resistant pancreatic cancer. Here, we synthesized three fluorescent dithiocarbazate–copper complexes

NIAID Data Ecosystem40

Supplementary Material for: Sustained clinical response to Olaparib in a patient with metastatic pancreatic cancer and somatic ATM-Mutation R2034Ter: a case report

胰腺癌治疗

PARP1抑制剂治疗

Background Pancreatic cancer remains a lethal disease with limited therapeutic options. The field of targeted therapies is still growing. Treatment with PARP inhibitors has been successfully described

DataCite Commons2025-06-01 更新80

Clinical outcomes of patients with pancreatic tumors discussed in Tumor Board

胰腺癌治疗

多学科肿瘤委员会决策评估

ABSTRACT Objective: the recommendations of the decisions made by the Tumor Board (TB) should be followed to identify barriers that may interfere with the execution of the previously decided, best care

Figshare2022-06-01 更新40

Activation of endogenous retroviruses and induction of viral mimicry by MEK1/2 inhibition in pancreatic cancer

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