Ruthenium(II)-Catalyzed Regioselective-Controlled Allenylation/Cyclization of Benzimides with Propargyl Alcohols
收藏NIAID Data Ecosystem2026-03-10 收录
下载链接：
https://figshare.com/articles/dataset/Ruthenium_II_-Catalyzed_Regioselective-Controlled_Allenylation_Cyclization_of_Benzimides_with_Propargyl_Alcohols/6463115
下载链接
链接失效反馈官方服务：
资源简介：
A ruthenium(II)-catalyzed
cyclization of benzimidates with substituted
propargyl alcohols to provide 3,4-disubstituted 1-alkoxy isoquinolines
in a highly selective manner via the C–H allenylation is described.
The proposed reaction mechanism of the ruthenium(II)-catalyzed cyclization
reaction is strongly supported by the isolation of the key ruthenacycle
intermediate, deuterium-labeling studies, and detailed DFT calculations
including the transition states.
创建时间：
2018-06-08
