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Crystal structure of HIV-1 reverse transcriptase in complex with RNA/DNA and Nevirapine

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Protein Data Bank Japan2023-09-20 更新2026-03-21 收录
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Crystal structure of HIV-1 reverse transcriptase in complex with RNA/DNA and Nevirapine Descriptor: 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE, 5'-D(*A*CP*AP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*GP*CP*GP*CP*CP*G)-3', 5'-R(P*AP*UP*GP*GP*UP*CP*GP*GP*CP*GP*CP*CP*CP*GP*AP*AP*CP*AP*GP*GP*GP*AP*CP*UP*GP*UP*G)-3', ... Authors: Das, K, Martinez, S.E, Arnold, E. Deposit date: 2014-03-13 Release date: 2014-06-18 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.901 Å) Cite: Structures of HIV-1 RT-RNA/DNA ternary complexes with dATP and nevirapine reveal conformational flexibility of RNA/DNA: insights into requirements for RNase H cleavage. Nucleic Acids Res., 42, 2014
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2014-03-13
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