Subject characteristics.

Baseline and follow-up means, displayed as geometric means with respective 95% confidence limits. Abbreviations: sTNF-R1: Soluble tumour necrosis factor-α receptor 1; hsCRP: High-sensitivity C-reactive protein; IL-6: Interleukin 6; eGFR: estimated glomerular filtration rate; BMI: Body mass index; Dia. BP: Diastolic blood pressure; Sys. BP: Systolic blood pressure; LDL: Low-density lipoprotein; HDL: High-density lipoprotein; PAD: Peripheral arterial disease. †p-values for mean differences between men and women (using T-test) or differences in numbers between men and women (using Fisher’s exact test); ** indicates p-values <0.0001 for baseline to follow-up change; * indicates p-values <0.05 for baseline to follow-up change. Subject characteristics.