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Systematic drug perturbations of cancer cells reveal diverse exit paths from the proliferative state

ChEBI2015-10-23 更新2026-07-12 收录

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细胞增殖调控

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-74281 数据链接链接失效反馈

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资源简介：

Systematic drug perturbations of cancer cells reveal diverse exit paths from the proliferative state

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创建时间：

2015-10-23

PARP-1靶向药物发现

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Poly (ADP-ribose) polymerase 1 (PARP-1) is a critical enzyme involved in DNA damage repair and recombination, and shows great potential for drug development in the treatment of cancers with defective

NIAID Data Ecosystem50

Different CAP parameter (output voltage and resistance value) effects for MSC growth in vitro.

细胞电刺激

细胞增殖调控

Note: “+” means positive effects (i.e., non-inhibited or increased cell proliferation when compared to untreated group) for MSCs; “−” means negative inhibited effects (i.e., decreased cell proliferati

Figshare2015-12-02 更新40

Thiazolation of phenylthiosemicarbazone to access new thiazoles: anticancer activity and molecular docking

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分子对接

Aim: Novel thiazole hybrids were synthesized via thiazolation of 4-phenylthiosemicarbazone (4). Materials & methods: The anticancer activity against the NCI 60 cancer cell line panel. Results: Methyl

NIAID Data Ecosystem10

NCI60 Transcriptome

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癌细胞分析

MRNA sequencing of the NCI60 cell lines

NIAID Data Ecosystem40

Transcriptome data of cancerous (HCT-116) and non-cancerous (IPEC-J2) intestinal cells treated with curcumin analogues

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转录组分析

This dataset contains RNA sequencing data of cancerous HCT-116 and non-cancerous intestinal IPEC-J2 cells treated with curcumin, three curcumin-based benzothiazepane analogues, and untreated controls.

NIAID Data Ecosystem10

Systematic drug perturbations of cancer cells reveal diverse exit paths from the proliferative state

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