Axial skeleton homeosis and forelimb malformations in Hoxd-11 mutant mice.
收藏PubMed Central1995-01-03 更新2026-05-16 收录
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https://pmc.ncbi.nlm.nih.gov/articles/PMC42868/
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资源简介：
The Hoxd-11 gene was disrupted by homologous recombination in embryonic stem cells. We found that Hoxd-11-/- mutant mice are viable and display homeotic transformations of their sacral vertebrae, while their forelimbs present abnormalities of some metacarpals and of the first row of carpal bones. These results are discussed in the light of current models of tetrapod axial skeleton and limb patterning. IMAGES:
提供机构：
National Academy of Sciences
创建时间：
1995-01-03
