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Diastereoselective Synthesis of γ‑Lactones through Reaction of Enediolates with α,β-Unsaturated Sulfoxonium Salts

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https://figshare.com/articles/dataset/Diastereoselective_Synthesis_of_Lactones_through_Reaction_of_Enediolates_with_Unsaturated_Sulfoxonium_Salts/2180761
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资源简介:
Studies of the reaction of lithium enediolates with α,β-unsaturated sulfoxonium salts are described. γ-Lactones were formed in very good to excellent yields (82% → 99% for 11 examples) and with very good to excellent diastereoselectivity (dr >90:10 for 10 examples), favoring the trans-diastereomer.
创建时间:
2016-02-13
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