Presence of 19A and 19F serotypes in both DpnI and DpnII populations.

*pneumococcal isolates represent assembled pneumococcal genomes. Dpn identity of other available sequenced pneumococcal genomes with known serotypes can be found in Table S1.
†capsule regulatory module identity determined by BLAST against wze sequence from blue and red references defined by Varvio and colleagues [21]. Values in brackets refer to % nucleotide sequence identity with D39 wze (blue module); followed by % identity with TIGR4 wze (red module).
‡Two S. mitis sequenced isolates arbitrarily chosen to demonstrate presence of both DpnI and DpnII systems in S. mitis population.
§87% identity to CSP2.