Dynamic regulation of T Follicular Regulatory (Tfr) cell responses by IL-2 during influenza infection
收藏NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE101016
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We found that approximately 2,000 genes were differentially expressed between conventional Treg and Tfr cells following influenza virus infection We conducted an RNA-seq analysis on sorted conventional Treg cells (FoxP3+CD69hiPD1loCXCR5loCD25hi) and Tfr cells (FoxP3+CD69hiPD1hiCXCR5hiCD25lo) obtained from the mediastinal lymph node (mLN) of day 30 infected B6.FoxP3-DTR/GFP mice. This analysis was performed to identify and quantify differentially-expressed genes and differentially-enriched signaling pathways between the two T cell subsets.
创建时间：
2021-07-25
