Four-Component Reaction for the Synthesis of Dithiocarbamates Starting from Cyclic Imines
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https://figshare.com/articles/dataset/Four-Component_Reaction_for_the_Synthesis_of_Dithiocarbamates_Starting_from_Cyclic_Imines/3483488
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资源简介:
An efficient one-pot,
four-component reaction for the synthesis
of dithiocarbamates using carbon disulfide, cyclic imines, acid chlorides,
and commercially available primary or secondary amines has been developed
by performing an acid chloride addition to a heterocyclic imine followed
by subsequent nucleophilic substitution of in situ generated dithiocarbamic
acid. With the aid of the newly developed and powerful multicomponent
reaction, a direct route for the synthesis of 24 unknown dithiocarbamates
in moderate to good yield under mild conditions is enabled.
创建时间:
2016-08-02



