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RNA sequencing data from 3T3 cells overexpressing hPARG

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NIAID Data Ecosystem2026-03-13 收录
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3T3 malignant cell line with stable overexpression of PARG under Doxycycline induction was generated. Transcriptome analysis linked malignance reduction phenotype with changes in chemokine family and other genes' expression levels. 3T3 cells were transduced with lentivirus construct encoding PARG cDNA with cleavable mClover3 under TetOne Doxycycline inducible promoter. Cells were plated to single well of 6 well plate, grown at 37°C in 5% CO2 for 72 hours without or with 500ng/ml Doxycycline and RNA isolated.

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2022-05-27
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