Back pocket flexibility provides group-II PAK selectivity for type 1 kinase inhibitors
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Back pocket flexibility provides group-II PAK selectivity for type 1 kinase inhibitors Descriptor: 1-{[1-(4-amino-1,3,5-triazin-2-yl)-2-methyl-1H-benzimidazol-6-yl]ethynyl}cyclohexanol, Serine/threonine-protein kinase PAK 4 Authors: Rouge, L, Tam, C, Wang, W. Deposit date: 2013-12-14 Release date: 2014-02-12 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (2.483 Å) Cite: Back Pocket Flexibility Provides Group II p21-Activated Kinase (PAK) Selectivity for Type I 1/2 Kinase Inhibitors. J.Med.Chem., 57, 2014
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2013-12-14
