Screen for Small-Molecule Modulators of Circadian Rhythms Reveals Phenazine as Redox-State Modifying Clockwork Tuner. Supplemental data.

<strong>Please use the following password to open the files in the PDF flies.rar folder: VanderbiltU8211</strong> -<strong>PDF file</strong> containing the Positive Hits identified as clock modulators in the high-throughput cell-based screen performed at Vanderbilt University. <br> Positive Hits were classified as: <br> a)<em>Long period</em>: compounds that lengthens the circadian period when compared to the DMSO control. b)<em>Short period</em>: compounds that shortens the circadian period when compared to the DMSO control. c)<em>Enhanced amplitude</em>: compounds that enhance the circadian amplitude when compared to the DMSO control. d)<em>Transient suppression</em>: compounds that suppress circadian cycles to later reach full recovery of the circadian oscillation when compared to the DMSO control. <br> In order to facilitate the result interpretation it is also included a “How to read instructions and examples” file.