P38 Kinase Crystal Structure in complex with RO3201195
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P38 Kinase Crystal Structure in complex with RO3201195 Descriptor: Mitogen-Activated Protein Kinase 14, [5-AMINO-1-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL](3-{[(2R)-2,3-DIHYDROXYPROPYL]OXY}PHENYL)METHANONE Authors: Harris, S.F, Bertrand, J, Villasenor, A. Deposit date: 2006-03-23 Release date: 2006-04-18 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.752 Å) Cite: Discovery of S-[5-Amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl]-[3-(2,3-dihydroxypropoxy)phenyl]-methanone (RO3201195), and Orally Bioavailable and Highly Selective Inhibitor of p38 Map Kinase J.Med.Chem., 49, 2006
创建时间:
2006-03-23



