Aging affects expression and variability of genes in the human liver. Aging affects expression and variability of genes in the human liver

Identification of genes altered by aging in the human liver We identified genes that were differentially expressed in males only, females only, or in all individuals between the young and old using microarray. Overall design: We compared gene expression profiles in liver samples from young (21-45 years) and old (69+ years) men and women to determine changes in the expression of xenobiotic metabolism enzymes and transporters.