Placental gene expression in two consecutive pregnancies

Differential gene expression was analyzed between in placenta from two consecutive pregnancies in from 10 women, in total 20 samples from BASIC study (Biological, Affect, Stress, Imaging, and Cognition in Pregnancy and the Puerperium), a population based prospective study at Uppsala University Hospital. Total tissue RNA was analyzed by use of Ion AmpliSeq Human Transcriptome Gene Expression kit.In addition to placental gene expression data is also available for the maternal health during pregnancy collected by use of questionnaires and medical records. Data availabilityCurrently, General Data Protection Regulation (GDPR), hinders data deposition of human genetic and sequencing data. The data and code used in this study are available from the authors upon reasonable request and with permission of BASIC study cohort. Contact [e-mail].

在乌普萨拉大学医院的基于人群的前瞻性研究中，对来自10名女性的连续两次妊娠的胎盘进行了差异基因表达分析，共收集了20个样本（BASIC研究：妊娠及产褥期的生物学、情感、压力、影像学和认知），该研究涉及妊娠期间的母体健康状况，通过问卷和病历收集。目前，由于通用数据保护条例（GDPR）的制约，阻碍了人类遗传和测序数据的存档。本研究中使用的数据和代码，在合理的请求和获得BASIC研究队列的许可后，可由作者提供。请联系[e-mail]获取。