BackgroundThe etiology of most premature ovarian failure (POF) cases is usually elusive. Although genetic causes clearly exist and a likely susceptible region of 8q22.3 has been discovered, no predomi
We specifically deleted Mettl3 in the female reproductive tract using the Pgr-Cre driver. To portray the molecular mechanism for Mettl3 function in oviduct, whole oviduct were collected from Mettl3f/f
The pituitary gonadotropins, follicle-stimulating hormone (FSH) and luteinizing hormone, signal the gonads to regulate male and female fertility. FSH is critical for female fertility as it regulates o