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Crystal Structure of 33 bound to CK2a

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Protein Data Bank Japan2026-05-27 更新2026-06-30 收录
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Crystal Structure of 33 bound to CK2a Descriptor: ACETATE ION, Casein kinase II subunit alpha, N~1~-[(2-chloro[1,1'-biphenyl]-4-yl)methyl]-N~4~-(2-{[(8P)-8-(1H-tetrazol-5-yl)benzo[c][2,6]naphthyridin-5-yl]amino}ethyl)butane-1,4-diamine Authors: Brear, P, Glossop, P, Pandey, S, Hyvonen, M, Spring, D, Butt, R, Cawkill, D. Deposit date: 2025-03-12 Release date: 2026-01-14 Last modified: 2026-05-27 Method: X-RAY DIFFRACTION (1.51 Å) Cite: Exploiting the Cryptic alpha D Pocket of Casein Kinase 2 alpha (CK2 alpha ) to Deliver Highly Potent and Selective Type 1 Inhibitors. J.Med.Chem., 68, 2025

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2025-03-12
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