GDF-15 and soluble ST2 as biomarkers ofright ventricular dysfunction in pulmonaryhypertension Supplementary Table 1
收藏Taylor & Francis Group2024-05-17 更新2026-04-16 收录
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https://tandf.figshare.com/articles/dataset/GDF-15_and_soluble_ST2_as_biomarkers_ofright_ventricular_dysfunction_in_pulmonaryhypertension_Supplementary_Table_1/22100906/1
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资源简介：
Background: This study analyzed the utility of soluble ST2 (sST2) and GDF-15 as biomarkers of right ventricular (RV) function in patients with pulmonary hypertension (PH). Methods: GDF-15 and sST2 serum concentrations were measured in patients with PH (n = 628), dilated cardiomyopathy (n = 31) and left ventricular hypertrophy (n = 47), and in healthy controls (n = 61). Results: Median sST2 and GDF-15 levels in patients with left ventricular hypertrophy were higher than in patients with PH and dilated cardiomyopathy. In tertile analysis GDF-15 >1363 pg/ml and sST2 >38 ng/ml were associated with higher N-terminal pro-brain natriuretic peptide, RV systolic dysfunction, RV-pulmonary arterial uncoupling and hemodynamic impairment. Conclusion: GDF-15 and sST2 are potential biomarkers of RV dysfunction in patients with PH.
提供机构：
Dorr, Oliver; Richter, Manuel J; Liebetrau, Christoph; Guth, Stefan; Voss, Sandra; Ghofrani, Hossein A; Seeger, Werner; Keller, Till; Jafari, Leili; Tello, Khodr; Nef, Holger; Wiedenroth, Christoph B; Kriechbaum, Steffen; Hamm, Christian W; Troidl, Christian; Bauer, Pascal; Keranov, Stanislav; Widmann, Laila; Gall, Henning
创建时间：
2023-02-15
