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Distinct Global Shifts in Genomic Binding Profiles of Limb Malformation Associated HOXD13 Mutations

ChEBI2013-08-19 更新2026-07-21 收录

基因调控机制

肢体发育疾病

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-44799 数据链接链接失效反馈

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资源简介：

Distinct Global Shifts in Genomic Binding Profiles of Limb Malformation Associated HOXD13 Mutations

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创建时间：

2013-08-19

基因调控机制

启动子功能

Despite extensive research, our understanding of the rules according to which cis-regulatory sequences are converted into gene expression is limited We devised a method for obtaining parallel, highly

NIAID Data Ecosystem80

Source Data Extended Data Figure 1c

染色体三维结构

基因调控机制

This file contains the source data for Extended Data Figure 1c. c, Hi-C matrix (at 5 kb resolution) and loops at the MRR1 region showing two looping silencers (S1 and S2) that exhibit chromatin intera

NIAID Data Ecosystem60

Crystal structure of the SAM-SAH riboswitch with adenosine.

RNA结构生物学

基因调控机制

Crystal structure of the SAM-SAH riboswitch with adenosine.

NIAID Data Ecosystem40

dCas9 Fusion to Computer Designed PRC2 Inhibitor Reveals Functional TATA Box in Distal Promoter Region [ChIP-seq]. dCas9 Fusion to Computer Designed PRC2 Inhibitor Reveals Functional TATA Box in Distal Promoter Region [ChIP-seq]

表观遗传学

基因调控机制

The critical process in development, bifurcation of cellular fates, requires epigenetic H3K27me3 marks propagated by PRC2 complex. However, the precise chromatin loci of functional H3K27me3 marks are

NIAID Data Ecosystem60

4C-seq protocol in mice macrophages

染色质构象

基因调控机制

A protocol for performing the 4C library and the analysis in mice macrophages. We used the ChIP-seq data to mark the DNA element regions (Silencer) and used the 4C-seq technique to investigate all the

NIAID Data Ecosystem50

Distinct Global Shifts in Genomic Binding Profiles of Limb Malformation Associated HOXD13 Mutations

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