five

Homo sapiens Exome. Homo sapiens

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NIAID Data Ecosystem2026-03-10 收录
下载链接:
https://www.ncbi.nlm.nih.gov/bioproject/PRJNA380993
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In this study we investigate the gene expressed profiles in 18 HCC cell lines with different metastatic potentials and organ-tropisms. Among them, HCC cell lines Huh7, Hep3B, SNU398, SMMC-7721,Bel-7402,HepG2,PLC-5 exhibit low metastasis abilities in nude mice model, while MHCC-97L, MHCC-97H, CSQT-1, CSQT-2, HCCLM3, LM1-S3, LM1-S4, LM1-S5, LM1-S11, LnM1-S11, LnM1-S13 exhibit high metastasis abilities in nude mice.LM1-S3, LM1-S4, LM1-S5, LM1-S11 derived from the parent cell line HCCLM3 have higher metastasis abilities specific to lung, and LnM1-S11, LnM1-S13 are specific to lymph node metastasis. We aim to explore differentially expressed genes involved in the process of HCC metastasis and organ-specific metastasis, and identify their biological functions.
创建时间:
2017-03-30
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