Escherichia coli small heat shock protein IbpA plays a role in regulating the heat shock response by controlling the translation of σ32
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Leucine differentially regulates gene-specific translation in mouse skeletal muscle. Mus musculus
Mice received an oral gavage of either leucine or vehicle, and quadriceps muscle were harvested for ribosome profiling or RNA-Seq analysis. Overall design: Gene expression analysis in the skeletal mus
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Autophagy-mediated Mir6981 degradation exhibits CDKN1B promotion of PHLPP1 protein translation
PHLPP1 (PH domain and leucine rich repeat protein phosphatase 1) is a newly identified family of Ser/Thr phosphatases that catalyzes the dephosphorylation of a conserved regulatory motif of the AGC ki
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Selective translation of nuclear mitochondrial respiratory proteins reprograms succinate metabolism in AML development and chemoresistance.[ChIP-seq]
Here we identify a novel RAS-responsive element binding protein 1 short isoform, RREB1S, as a key in governing mitochondrial complex II translation to promote stemness and drug resistance of cancer st
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High resolution ribosome profiling reveals gene-specific details of UGA recoding in selenoprotein biosynthesis. High resolution ribosome profiling reveals gene-specific details of UGA recoding in selenoprotein biosynthesis
SECIS binding protein 2 (SECISBP2) increases the efficiency of recoding of UGA codons as selenocysteine (Sec) during translation of mRNAs containing a selenocysteine insertion sequence (SECIS) in the
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Lin28-mediated promotion of protein synthesis is critical for neural progenitor cell maintenance and brain development in mice. Lin28-mediated promotion of protein synthesis is critical for neural progenitor cell maintenance and brain development in mice
Neural progenitor cells (NPCs) undergo rapid proliferation during neurulation in early development. This rapid growth generates a high demand for mRNA translation in a timing-dependent manner, but its
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