NEW EMBO MEMBER’S REVIEW
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NEW EMBO MEMBER’S REVIEW
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2001-09-03
相关数据集
Yeast Hct1 recognizes the mitotic cyclin Clb2 and other substrates of the ubiquitin ligase APC
Ubiquitin-mediated proteolysis has emerged as a key mechanism of regulation in eukaryotic cells. During cell division, a multi-subunit ubiquitin ligase termed the anaphase promoting complex (APC) targ
PubMed Central2001-09-17 更新40
Ca(2+) sensor S100β-modulated sites of membrane guanylate cyclase in thephotoreceptor-bipolar synapse
This study documents the identity of a calcium- regulated membrane guanylate cyclase transduction system in the photoreceptor-bipolar synaptic region. The guanylate cyclase is the previously character
PubMed Central2002-06-03 更新10
Atomic structure of the major capsid protein of rotavirus: implications for the architecture of the virion
The structural protein VP6 of rotavirus, an important pathogen responsible for severe gastroenteritis in children, forms the middle layer in the triple-layered viral capsid. Here we present the crysta
PubMed Central2001-04-02 更新10
DNA polymerase β is the major dRP lyase involved in repair of oxidative base lesions in DNA by mammalian cell extracts
The repair of oxidative base lesions in DNA is a coordinated chain of reactions that includes removal of the damaged base, incision of the phosphodiester backbone at the abasic sugar residue, incorpor
PubMed Central2001-12-03 更新10
CREB activation induced by mitochondrial dysfunction is a new signaling pathway that impairs cell proliferation
We characterized a new signaling pathway leading to the activation of cAMP-responsive element-binding protein (CREB) in several cell lines affected by mitochondrial dysfunction. In vitro kinase assays
PubMed Central2002-01-15 更新10
