Ptprf

ENCODES a protein that exhibits insulin receptor binding; phosphate ion binding; protein tyrosine phosphatase activity; INVOLVED IN homophilic cell adhesion via plasma membrane adhesion molecules; negative regulation of cell population proliferation; negative regulation of cell projection organization; PARTICIPATES IN insulin signaling pathway; ASSOCIATED WITH obesity; Aplasia or Hypoplasia of Breasts and/or Nipples 2 (ortholog); Charcot-Marie-Tooth disease dominant intermediate C (ortholog); FOUND IN endosome; excitatory synapse; growth cone; INTERACTS WITH (+)-schisandrin B; 1,3-dinitrobenzene; 17beta-estradiol

编码一种表现出胰岛素受体结合、磷酸离子结合、蛋白酪氨酸磷酸酶活性特征的蛋白质；参与通过质膜粘附分子介导的同源细胞粘附；调节细胞群体增殖的负性调控；调节细胞突起组织的负性调控；参与胰岛素信号通路；与肥胖相关；涉及乳腺或乳晕发育不良2号（同源物）；查尔科-玛丽-图奥特病显性中间型C（同源物）；存在于内吞体、兴奋性突触、生长锥中；与（+）川楝素B、1,3-二硝基苯、17β-雌二醇相互作用。