Alignment of microvesicle non-coding RNA to repeat regions.

Repeat class was defined by the UCSC repeatMasker dataset [12] and the number of known repeats listed under ‘# known’. All repeat classes were found in microvesicles and the number of hits and percentage hits are shown for each sample, with DNase treatment (+DNase) (RNA sample) and without DNase treatment (-DNase) (RNA+DNA sample). SINE-Short interspersed nuclear elements (which include ALUs), LINE-Long interspersed nuclear elements, LTR-Long terminal repeat elements (which include retrotransposons), DNA repeat elements, Simple repeats (micro-satellites), Low complexity repeats, Satellite repeats, RNA repeats (which includes RNA, rRNA – ribosomal RNA, scRNA – small cytoplasmic RNA, snRNA – small nuclear RNA, srpRNA – signal recognition particle RNA, tRNA – transfer RNA), Other repeats (including Rolling Circle (RC)) were detected within the non-ORF reads of microvesicles and presented as hits and % hits detected.