Disentangling synergistic disease dynamics: Implications for the viral biocontrol of rabbits
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European rabbits (Oryctolagus cuniculus) have been exposed to rabbit haemorrhagic disease virus (RHDV) and myxoma virus (MYXV) in their native and invasive ranges for decades. Yet, the longâterm effects of these viruses on rabbit population dynamics remain poorly understood. In this context, we analysed 17 years of detailed captureâmarkârecapture data (2000â2016) from Turretfield, South Australia, using a probabilistic stateâspace hierarchical modelling framework to estimate rabbit survival and epidemiological dynamics. While RHDV infection and diseaseâinduced death were most prominent during annual epidemics in winter and spring, we found evidence for continuous infection of susceptible individuals with RHDV throughout the year. RHDVâsusceptible rabbits had, on average, 25% lower monthly survival rates compared to immune individuals, while the average monthly force of infection in winter and spring was ~38%. These combined to result in an average infectionâinduced mortality rate ...



