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Heterogeneity of alternative splicing in melanoma

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NIAID Data Ecosystem2026-05-01 收录
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Alternative splicing of BRAF mRNA can provide a resistance mechanism to BRAF and MEK inhibitors in BRAF-mutant melanoma. The study goal is to understand the mechanism underlying the production of different BRAF isoforms. To do this, we performed whole-genome sequencing of BRAF-mutant cell melanoma cell lines, resistant to MAPK inhibitors.

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2023-08-05
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